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Changes in the DENND1B gene increase the risk of childhood asthma
  1. S Haney
  1. Correspondence to S Haney, Wansbeck Hospital, Northumbria, UK; sas_haney{at}yahoo.co.uk

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Previous studies have shown associations between asthma and single nucleotide polymorphisms (SNPs) on the 17q12 chromosome, but the risk associated with these SNPs is low.

This study used children of European ancestry as a ‘discovery set’. Genome-wide association identified several SNPs in the 1q31.3 region associated with childhood onset asthma (typical …

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