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Utility of serum and sputum calprotectin as a biomarker for CF exacerbation
  1. Irfan Shafiq
  1. Correspondence to Dr Irfan Shafiq, Cystic Fibrosis Unit, Southampton General Hospital, Tremona road, Southampton SO16 6YD, UK; irfanshafiq{at}gmail.com

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Monitoring inflammation and diagnosing pulmonary exacerbation in cystic fibrosis (CF) remains difficult as the usual biomarkers of inflammation are often not very helpful and there is still no accepted definition for a CF exacerbation. This study looked at the possibility of serum and sputum calprotectin as a new biomarker for monitoring pulmonary exacerbations in CF.

It was hypothesised that serum and …

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