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Presence of MBL in airways: is it a disease severity marker or an additional host defence mechanism?
  1. K C Jambo,
  2. S B Gordon
  1. Pulmonary Immunology Group, Liverpool School of Tropical Medicine, Liverpool, UK
  1. Correspondence to K C Jambo, Pulmonary Immunology Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK; kjambo{at}

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We welcome the paper by Fidler and colleagues reporting the presence of mannose-binding lectin (MBL) in infected airways.1 MBL is an important acute phase protein with pro- and anti-inflammatory immunomodulatory functions.2 The collectin family comprises surfactant protein (SP)-A, SP-D and MBL, of which the latter is mostly present in peripheral blood while the other two are mostly located in the lung.3 We agree with Fidler et al that MBL …

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  • Funding This article has been written with funding from the Wellcome Trust and Commonwealth Scholarship Commission.

  • Competing interests None.

  • Provenance and Peer review Not commissioned; not externally peer reviewed.

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