Article Text

Download PDFPDF
Extracorporeal carbon dioxide removal to “protect” the lung
  1. S L Stirling,
  2. J J Cordingley,
  3. D N Hunter,
  4. M J Griffiths,
  5. S J Wort,
  6. T W Evans,
  7. S J Finney
  1. Adult Intensive Care Unit, Royal Brompton Hospital, London, UK
  1. Dr S J Finney, Adult Intensive Care Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK; s.finney{at}


The case histories are presented of three adults who had severe hypercapnic acidosis despite mechanical ventilation with what were considered to be injurious tidal volumes and airway pressures. The use of a percutaneously inserted arteriovenous extracorporeal carbon dioxide removal (AV-ECCO2R) device facilitated a dramatic reduction in the amount of ventilatory support required, achieving a “lung-protective” level. Two patients survived to hospital discharge. One patient died after it became apparent that her late-stage interstitial lung disease was unresponsive to immunosuppression. AV-ECCO2R may be a useful strategy in facilitating lung-protective ventilation.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: None.

  • Patient consent: Obtained.