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A woman in her mid 30s with a dry cough and breathlessness
  1. H K Ramadan1,
  2. C I Mackinlay2,
  3. A G Nicholson3
  1. 1
    Respiratory Department, Royal Hampshire County Hospital, Winchester, UK
  2. 2
    Respiratory Department, Great Western Hospital, Swindon, UK
  3. 3
    Histopathology Department, Royal Brompton Hospital, London, UK
  1. Dr H K Ramadan, Respiratory Department, Royal Hampshire County Hospital, Winchester SO22 5DG, UK; hkhk00{at}

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A female non-smoker in her thirties was referred to the chest clinic with a 6-month history of a dry cough, breathlessness and general malaise.

Her chest x ray showed diffuse bilateral ground-glass opacity (fig 1). Her autoimmune profile was negative. An HIV test was negative. Lung function tests showed a restrictive pattern with moderately reduced transfer factor.

Figure 1

Chest x ray: diffuse bilateral ground-glass opacity.

A high resolution CT (HRCT) showed bilateral ground-glass opacity, more marked on the right, with no evidence of mediastinal or hilar lymphadenopathy (fig 2).

Figure 2

High …

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