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Pathogenetic mechanisms involved in viral-induced exacerbations of COPD
  1. A Singanayagam
  1. Dr A Singanayagam, Speciality Trainee Year 2, Churchill Hospital, Oxford, UK;
  1. Dr A Singanayagam

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Viruses have been shown to be important causes of exacerbations in patients with chronic obstructive pulmonary disease (COPD). Evidence suggests that innate immune responses play a key role in the pathogenesis of airway inflammation in cigarette smoke (CS)-exposed individuals. However, the precise immune pathways and viral pathogen-associated molecular patterns that trigger these responses have not been …

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