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A non-invasive technique to genotype lung cancer cells
  1. A Cheong
  1. Dr A Cheong, Specialty Registrar, Royal Brompton Hospital, London, UK; Adrian{at}cheong.org.uk

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Mutations in the epithelial growth factor receptor (EGFR) are thought to occur early in the oncogenesis of non-small cell lung carcinoma (NSCLC). This paper describes the use of a novel chip to capture circulating tumour cells (CTCs) combined with a “SARMS” (Scorpion Amplification Refractory Mutation System) allele-specific genotyping assay to detect EGFR mutations.

The study …

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