Thank you for giving us an opportunity to comment on the letter by Añon and Garcia de Lorenzo. We agree that further information about patients on long-term oxygen therapy (LTOT) is important, especially as, anecdotally, some clinicians seem to consider LTOT to be an absolute contraindication to intubation. Table 1 summarises the outcomes for intubated patients with chronic obstructive pulmonary disease (COPD) in the COPD and Asthma Outcome Study …