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Clinically significant outcomes in smoking cessation
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The study by Aubin et al1 published in this issue comparing varenicline with nicotine replacement therapy (NRT). The authors have shown a significant difference in continuous abstinence rate at the end of treatment of 12 (or 11) weeks, favouring varenicline. However, the beneficial effect is not maintained in a significant fashion up to the end of the study period at 52 weeks. In …
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Competing interests: None.