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Neuropilin 1 is important in NSCLC
  1. Tim Jones
  1. T Jones, Specialist Registrar, Glan Clwyd Hospital, Rhyl, Denbighshire, UK; doctortimjones{at}hotmail.com

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Neuropilin 1 (NRP1) is a neuronal receptor that mediates angiogenesis and lung branching during embryonic development and promotes tumour angiogenesis. Its role in cancer progression is not clear. This study examined the role of NRP1 in cancer invasion and angiogenesis, its signalling pathways and prognostic significance in non-small cell lung cancer (NSCLC).

Sixty consecutive patients …

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