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Revival of carbocisteine for prevention of COPD exacerbations
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  1. P Parulekar,
  2. A Yavari
  1. Dr P Parulekar, ST3, Northampton General Hospital, Northampton NNI SBD, UK; prashantparulekar{at}yahoo.co.uk

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    This Chinese multicentre double-blind study assessed whether carbocisteine, a mucolytic agent with antioxidant and anti-inflammatory properties, could reduce exacerbation rates in patients with chronic obstructive pulmonary disease (COPD). A total of 709 patients with COPD were randomised to receive 1500 mg carbocisteine or placebo daily for 1 year. The patients …

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