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  1. M T Dransfield,
  2. S M Rowe,
  3. J Johnson,
  4. W Bailey,
  5. L Gerald
  1. University of Alabama at Birmingham and the Birmingham VA Medical Center, Birmingham, Alabama, USA
  1. Dr M T Dransfield, University of Alabama at Birmingham and the Birmingham VA Medical Center, 215 THT 1900 University Blvd, Birmingham, AL 35294, USA; mdransfield99{at}msn.com

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We appreciate Dr Singh’s interest in our paper and the thoughtful comments. While we believe our data make a compelling argument that β blockers are regularly tolerated by patients suffering acute exacerbations of COPD and that they may be associated with improved outcomes, we do not advocate their routine use at present and believe this overstates our conclusions.1 We echo Dr Singh’s call for randomised clinical trials in a variety of settings to definitively address the safety …

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