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Mannose-binding lectin deficiency increases mortality risk from pneumococcal infection
  1. R M Jones
  1. Dr R M Jones, Clinical Research Fellow, Morriston Hospital, Swansea, UK; drmatjones{at}hotmail.com

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    Low serum levels or genotypic variants of the innate immune molecule mannose-binding lectin (MBL) have been associated with increased susceptibility to infectious diseases. Few studies of MBL have included sufficiently large sample sizes and conclusions drawn have been conflicting. This study set out to reanalyse existing data from studies on MBL in order to define the serum level of MBL deficiency and determine the …

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