Article Text

This article has a correction. Please see:

PDF

Pulmonary veno-occlusive disease presenting with recurrent pulmonary oedema and the use of nitric oxide to predict response to sildenafil
  1. B C Creagh-Brown1,
  2. A G Nicholson2,
  3. R Showkathali3,
  4. J S R Gibbs3,
  5. L S G E Howard3
  1. 1
    Royal Brompton Hospital, London, UK
  2. 2
    Royal Brompton Hospital, London, UK
  3. 3
    National Pulmonary Hypertension Service, Department of Cardiac Sciences, The Hammersmith Hospitals NHS Trust, London, UK
  1. Dr B C Creagh-Brown, St George’s Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK; drbencb{at}gmail.com

Abstract

Pulmonary veno-occlusive disease (PVOD) is a disorder which causes progressive pulmonary hypertension, usually presenting with worsening dyspnoea and right heart failure. Pulmonary oedema induced by pulmonary vasodilator therapy to reduce pulmonary arterial pressure has been well described in PVOD, but here we describe a case of PVOD presenting with recurrent episodes of acute non-cardiogenic pulmonary oedema, in the absence of significant pulmonary hypertension. Concern over the risk of precipitating pulmonary oedema led us to use inhaled nitric oxide to predict the safety and efficacy of sildenafil.

Statistics from Altmetric.com

Footnotes

  • Competing interests: None.

  • Patient consent: Obtained from the patient's next of kin.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Airwaves
    Wisia Wedzicha
  • Correction
    BMJ Publishing Group Ltd and British Thoracic Society