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Inhaled corticosteroids (ICS) are standard treatment for persistent asthma but it is important to “step down” treatment when possible to minimise adverse effects. The optimal strategy for reducing treatment in mild asthma has not yet been determined.
Five hundred patients with mild asthma (pre-bronchodilator FEV1 >60% predicted) well controlled on 4–6 weeks fluticasone 100 μg twice …