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Strategies for reducing treatment in mild persistent asthma
  1. Andrew Medford
  1. Respiratory Specialist Registrar, Derriford Hospital; andrewmedford@hotmail.com

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    ▴ American Lung Association Asthma Clinical Research Centers, Peters SP, Anthonisen N, et al. Randomised comparison of strategies for reducing treatment in mild persistent asthma. N Engl J Med2007;356:2027–39.
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    Inhaled corticosteroids (ICS) are standard treatment for persistent asthma but it is important to “step down” treatment when possible to minimise adverse effects. The optimal strategy for reducing treatment in mild asthma has not yet been determined.

    Five hundred patients with mild asthma (pre-bronchodilator FEV1 >60% predicted) well controlled on 4–6 weeks fluticasone 100 μg twice …

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      Anna Rich David Baldwin Richard Hubbard
      Thorax 2012; 67 927-927 Published Online First: 14 Feb 2012. doi: 10.1136/thoraxjnl-2012-201655