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Combination treatment may help patients with COPD, but does not improve mortality
  1. Sundari Ampikaipakan
  1. Specialist Registrar in Respiratory Medicine, Norfolk and Norwich University Hospital;

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This multicentre, randomised, double blind trial comparing the combination of salmeterol and fluticasone propionate 50/500μg twice daily with placebo, salmeterol alone or fluticasone alone was carried out over a period of 3 years. Subjects included current or ex-smokers with at least a 10-pack year history, a diagnosis of chronic obstructive pulmonary disease (COPD) and a prebronchodilator forced …

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