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Is physical activity anti-inflammatory on the airways?
  1. Donald A Mahler
  1. Correspondence to:
    Dr Donald A Mahler
    Section of Pulmonary and Critical Care Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756-0001, USA; Donald.a.mahler{at}

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Further evidence that physical activity may prevent or modify airway inflammation

In this issue of Thorax (see p 403), Shaaban and colleagues1 report an inverse relationship between weekly exercise and bronchial hyperresponsiveness (BHR) in 5518 adults. Participants answered questionnaires on whether “they usually exercised so much that they got out of breath or sweaty” in order to estimate weekly frequency and duration of physical activity. Although this methodology may be difficult to validate, self-report questionnaires are used routinely to obtain information in epidemiological studies. These findings are consistent with the results of two previous studies: Rasmussen and coworkers2 found that decreased physical fitness in childhood was significantly correlated with the development of adolescent asthma over a 10 year period, and Huovinen et al3 showed in a 17 year study of 262 twins that the …

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