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Occupational eosinophilic bronchitis in a foundry worker exposed to isocyanate and a baker exposed to flour
  1. Fabio Di Stefano,
  2. Luca Di Giampaolo,
  3. Nicola Verna,
  4. Mario Di Gioacchino
  1. Department of Medicine and Science of Ageing, Section of Allergy, Clinical Immunology and Occupational Medicine, University “G D’Annunzio”, Chieti, Italy
  1. Correspondence to:
    Dr F Di Stefano
    Respiratory Medicine, Presidio Ospedaliero “G Bernabeo”, C da S Liberata, 66026 Ortona (Chieti), Italia; distefa.fabio{at}tiscali.it

Abstract

Eosinophilic bronchitis without asthma may occur as a consequence of occupational exposure. The cases of a foundry worker and a baker who developed symptoms, respectively, due to exposure to isocyanate and flour, are reported. Cough was not associated with variable airflow obstruction or with airway hyper-responsiveness and was responsive to inhaled corticosteroids. The eosinophilia detectable in their sputum was causally related to the occupational exposure in the workplace. The examination of induced sputum should be used in addition to the objective monitoring of lung function for workers who have asthma-like symptoms in an occupational setting.

  • FEV1, forced expiratory volume in 1 s
  • MDI, methylene diphenyl isocyanate

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