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Folate metabolism gene polymorphisms may influence lung cancer prognosis
  1. Marie Fisk
  1. FY2, Broomfield Hospital, Chelmsford; mariefisk{at}hotmail.com

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▴ Matakidou A, el Galta R, Rudd MF, et al. Prognostic significance of folate metabolism polymorphisms for lung cancer. Br J Cancer 2007;97:247–52.

Aberrant DNA methylation is a common feature of human neoplasia, including lung cancer. Folate metabolism pathway variants affect DNA methylation and tumour suppressor genes and may impact tumour …

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