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Inhaled corticosteroids and adrenal suppression in children
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  1. J Steer
  1. Specialist Registrar in Respiratory Medicine, Hartlepool, UK; john_steer@hotmail.com

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    ▴ Paton J, Jardine E, McNeill E, et al. Adrenal responses to low dose synthetic ACTH (Synacthen) in children receiving high dose inhaled fluticasone. Arch Dis Child2006;91:808–13.
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    Inhaled corticosteroids (ICS) have been shown to cause clinical adrenal insufficiency. Following two serious cases of acute adrenal insufficiency due to ICS, Paton et al evaluated adrenal function in children prescribed fluticasone proprionate above the maximum UK licensed dose (>400 μg/day).

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