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Further scientific evidence for the usefulness of signs and symptoms in predicting a specific cause of chronic cough in children
Problem coughing is common in children and can be produced by almost all the respiratory disorders that affect them. Rather than applying a comprehensive battery of tests to all children, most doctors use clinical pointers in the history and examination to determine the need for and targeting of investigations. Indeed, experienced clinicians usually use more than one single feature or diagnostic test and bring together bits of the history, clinical examination, and selective investigative tests to arrive at a diagnosis. Typical clinical cues recommended to be used in evaluating cough include (1) age of symptom onset, (2) quality of the cough, (3) triggers, periodicity and timing of cough, and (4) associated features such as wheezing.1
Recent evidence suggests that parents do not report the frequency or severity of cough accurately.2,3 However, work from Professor Chang’s unit has shown that parental reporting of wet versus dry cough is likely to be accurate.4 Most of the clinical characteristics or pointers used to predict specific diseases causing cough in children have not been rigorously subjected to assessment as would be required for a diagnostic test …
Footnotes
Conflict of interest: In the last 12 months the author has received honoraria by Merck Sharp & Dohme and GlaxoSmithKline for lectures given and attended an advisory board meeting for Altana. In the past 5 years he hase given lectures and attended conferences as a guest for AstraZeneca, GlaxoSmithKline, Merck Sharp & Dohme, and 3M.