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Association between sibship size and allergic diseases in the Glasgow Alumni Study
  1. R M D Bernsen1,
  2. J C van der Wouden2
  1. 1Department of Community Medicine, United Arab Emirates University, Al Ain, United Arab Emirates
  2. 2Department of General Practice, Erasmus MC – University Medical Center, Rotterdam, The Netherlands
  1. Correspondence to:
    Dr R M D Bernsen
    Department of Community Medicine, United Arab Emirates University, P O Box 17666, Al Ain, United Arab Emirates; roos.bernsen{at}uaeu.ac.ae

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    We read the interesting study by Kinra et al1 which gives us important information on the relationship between sibship size, birth order, and allergic disease in British students born in the first half of the 20th century. There are, however, a few points which we would like to raise:

    (1) The authors observed a stronger association between sibship size and allergy in the oldest cohort and interpreted this finding as supporting the hygiene hypothesis because of a postulated larger difference in hygiene between larger and smaller families in this …

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    Footnotes

    • Competing interests: none

    • Dr Kinra was asked to comment, but no reply was received by the time this issue of Thorax went to press.