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Matrix metalloproteinases in destructive pulmonary pathology
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  • Published on: 21 March 2006
    Complexities of pulmonary dysfunction following cardiopulmonary bypass
    • Calvin S.H. Ng, Cardiothoracic Surgeon
    • Other Contributors:
      • Song Wan, Malcolm J. Underwood, Anthony P.C. Yim

    Dear Editor,

    We congratulate Elkington and Friedland on their excellent review which gives an overview of matrix metalloproteinases (MMPs) in various destructive pulmonary diseases.[1] MMPs and neutrophil elastase do indeed play instrumental roles in the development of ARDS and lung injury following cardiopulmonary bypass (CPB), however, the mechanisms presented may be too simplified.[2]

    Apart from...

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    Conflict of Interest:
    None declared.