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Clinical efficacy of anti-pneumococcal vaccination in patients with COPD
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    Doubting the efficacy of pneumococcal vaccination

    Dear Editor,

    I read with interest the paper by Alfageme and colleagues (1) who investigated the efficacy of anti-pneumococcal vaccination in patients with COPD. To have new data in an area which has suffered from a surfeit of meta-analysis and even analysis of the meta-analysis is good and their results are quite clear. Although they do not specifically comment I presume that their primary end point was accum...

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    Conflict of Interest:
    None declared.