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No further tests for PE required in low probability cases with a negative D-dimer test
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  1. N Bari
  1. Specialist Registrar in Respiratory Medicine, Royal London Hospital, London, UK; nabeelab@hotmail.com

https://doi.org/10.1136/thx.2006.la0228

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    ▴ Kearon C, Ginsberg JS, Douketis J, et al for the Canadian Pulmonary Embolism Study Group. An evaluation of D-dimer in the diagnosis of pulmonary embolism. Ann Intern Med2006;144:812–21
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    In patients with suspected pulmonary embolism (PE), further diagnostic testing is often omitted on the basis of a negative D-dimer test result. This study is the first randomised controlled trial to evaluate this approach.

    1126 randomised patients with suspected PE were evaluated and classified into low (group A) and high (group B) clinical probability groups; 456 with …

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