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Progression of lung disease on computed tomography and pulmonary function tests in children and adults with cystic fibrosis
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  • Published on:
    The authors’ response to Dr Quanjer

    Dear Editor,

    We appreciate the comments made by Prof. Quanjer concerning our manuscript (1) and fully agree with his comments. In his letter to the editor Prof. Quanjer gives valuable background information to the reasons why pulmonary function tests are relatively insensitive to track pulmonary changes in the longitudinal follow up of cystic fibrosis (CF) lung disease (2). We agree with his arguments that this is...

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    Conflict of Interest:
    None declared.
  • Published on:
    Pulmonary function tests in following up cystic fibrosis

    I read with great interest the paper by de Jong et al. [1]. The authors conclude from a carefully conducted study that scores derived from CT scans are more sensitive in detecting progression of cystic fibrosis in children and adults than pulmonary function tests. I have no difficulty in accepting any such outcome. However, it seems that undue reliance was placed on predicted pulmonary indices, and...

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    Conflict of Interest:
    None declared.