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Nortriptyline may help in smoking cessation
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  1. H E Davies
  1. Specialist Registrar, Wycombe Hospital, Buckinghamshire, UK; hedavies@doctors.net.uk

https://doi.org/10.1136/thx.2004.la0140

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    ▴ Prochazka AV, Kick S, Steinbrunn C, et al. A randomized trial of nortriptyline combined with transdermal nicotine for smoking cessation. Arch Intern Med 2004;164:2229–33
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    This double blind, randomised, controlled trial compared smoking cessation rates of nortriptyline with placebo in addition to transdermal nicotine and a behavioural smoking cessation programme. 158 subjects aged 18–65 years were enrolled, all of whom smoked 10 or more cigarettes daily. Nortriptyline (25 mg/day, titrated up to 75 mg/day as tolerated) or matched …

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