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Prostanoid DP receptor polymorphisms may cause changes in susceptibility to asthma
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  1. C Prys-Picard
  1. Clinical Research Fellow, North West Lung Centre, Manchester, UK; cpryspicard@fs1.with.man.ac.uk

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Prostaglandins have been implicated in the pathophysiology of asthma. The prostaglandin receptor is expressed on the surface of airway eosinophils and mast cells. This group has studied the gene for the prostanoid DP receptor (PTGDR) and its relationship with the asthma phenotype.

Screening revealed four new single nucleotide polymorphisms …

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