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Vitamin E supplements in asthma: a parallel group randomised placebo controlled trial
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  • Published on:
    Re: Effects of vitamin E in mild-to-moderate asthmatics
    • Andrew W Fogarty, Lecturer in Respiratory Medicine
    • Other Contributors:
      • Philip Pearson, John Britton

    Dear Editor

    The aim of our study was to study ‘the effect of 6 weeks regular supplementation with vitamin E on the clinical control of asthma’ [1]. We thus used a combination of objective and subjective measures of asthma as our outcomes. The entry criteria were designed to be as inclusive as possible and to cover a population with mild to moderate asthma.

    However, as Currie et al highlight our study pop...

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    Conflict of Interest:
    None declared.
  • Published on:
    Effects of vitamin E in mild-to-moderate asthmatics

    Dear Editor

    Pearson et al [1] have failed to tease out any additional benefit of vitamin E supplementation in mild-to-moderate asthmatics. Before concluding that this is the case, it is relevant to highlight several points in their study.

    It is notable that the authors failed to measure any surrogate marker of inflammation such as exhaled nitric oxide, sputum eosinophils or airway hyperresponsiveness (AHR)...

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    Conflict of Interest:
    None declared.