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Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough
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  • Published on:
    Authors' response

    Dear Editor

    We thank Professor Morice and his colleagues for their interest and for the issues raised vis-a-vis our manuscript.

    The main issue raised concerns the possibility that we may have missed gastrooesophageal disorders such as reflux and dysmotility in our cohort of chronic cough patients. In our assessment protocol, we state that we used oesophageal pH measurements in most patients (32 out of 50)...

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    Conflict of Interest:
    None declared.
  • Published on:
    Exhaled breath condensate in chronic cough
    • Alyn H Morice
    • Other Contributors:
      • Caroline F Everett, Siobhan A Mulrennan

    Dear Editor

    We read with interest the recent article by Niimi et al reporting low levels of exhaled breath condensate (EBC) pH in patients with chronic cough [1]. We and others have described low EBC pH in association with airway inflammation in allergic asthma, cystic fibrosis and COPD [2][3][4]. In these studies there is a relatively close association between inflammation and low pH which is shown by the furth...

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    Conflict of Interest:
    None declared.