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Do inhaled corticosteroids slow FEV1 decline in COPD after all?
  1. M G Duerden
  1. Department of Medicines Management, Keele, University, Staffordshire ST5 5BG, UK; martin@theduerdens.co.uk

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I question the findings of the meta-analysis by Sunderland et al1 and the content of the associated editorial by Burge and Lewis.2 The meta-analysis has drawn from available long term data from randomised controlled studies (RCTs) of inhaled corticosteroids (ICS) in chronic obstructive airways disease (COPD). The whole purpose of meta-analysis is to analyse such data systematically to answer a question. This study seems to use the data selectively to demonstrate an effect. Another recent meta-analysis—in my …

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