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Airway obstruction and autoimmunity
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Birring and colleagues have shown an interesting link between respiratory symptoms and autoimmunity in the form of both hypothyroidism and Crohn’s disease.1 In addition, they have previously demonstrated a link between autoimmune disease and airway obstruction in non-smokers.2 We have reported a similar association between airway obstruction and rheumatoid arthritis with a 2–3-fold increased prevalence of wheeze and physiological abnormalities in patients with rheumatoid arthritis compared with controls with osteoarthritis.3
Our group has also found …