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Tuberculosis and anti-TNF-α treatment
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  • Published on: 29 April 2016
    Tuberculosis screening and anti-TNF-alpha therapy

    Dear Editor

    Reactivation of tuberculosis (TB) is a major concern during treatment with TNF inhibitors [1]. Different guidelines to detect active and latent TB have been reccomended in various countries before starting therapy with these drugs. There is evidence that their application has led to a significant reduction in the number of cases of TB [2], but we do not know which is the most cost-effective strategy. At...

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    Conflict of Interest:
    None declared.
  • Published on: 29 April 2016
    Tuberculosis and anti-TNF- treatment
    • Prasanta Raghab Mohapatra, Senior Lecturer, Dept. of Tuberculosis and Respiratory Medicine
    • Other Contributors:
      • Ashok Kumar Janmeja.

    Dear Editor

    Anti TNF treatment should be given after screening for latent tuberculosis as this may result active tuberculosis in these cases [1]. The World Health Organization estimates that at least one-third of the world’s population are infected with TB [2], [3]. 95% of tuberculosis cases and 98% tuberculosis deaths are in the developing countries [2], [3]. It is difficult to rule out latent tuberculosis infection...

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    Conflict of Interest:
    None declared.