Article Text

Download PDFPDF

Preliminary experience with a new method of endoscopic transbronchial real time ultrasound guided biopsy for diagnosis of mediastinal and hilar lesions
  1. M Krasnik,
  2. P Vilmann,
  3. S S Larsen,
  4. G K Jacobsen
  1. Department of Cardiothoracic Surgery R and Department of Surgical Gastroenterology D, Gentofte University Hospital, Niels Andersens Vej 65, 2900 Hellerup, Denmark
  1. Correspondence to:
    Dr P Vilmann
    Department of Surgical Gastroenterology D, Gentofte University Hospital, Niels Andersensvej 65, 2900 Hellerup, Denmark; pevigentoftehosp.kbhamt.dk

Abstract

Background: The aim of the present study was to gain experience with a new method of endoscopic transbronchial ultrasonography with direct, real time guided fine needle aspiration biopsy (EBUS-FNA).

Methods: EBUS-FNA was performed in 11 patients. Selection of the patients for EBUS-FNA was based on computed tomographic (CT) scanning in 10 patients and on positron emission tomography in one. The ultrasonic bronchoscope used was a prototype with an outer diameter of 6.9 mm. The instrument has a small curved array transducer located in front of a 30° oblique forward viewing optic lens and a biopsy channel of 2 mm. The procedures were performed under general anaesthesia. EBUS-FNA was performed by direct transducer contact with the trachea or main bronchi with a prototype 22 gauge needle.

Results: A total of 15 lesions were punctured. No complications were experienced. Four lesions were targeted in region 10L, four in region 10R, one in region 4L, three in region 4R, one in region 1, one in region 7, and one in region 2R. The size of the lesions ranged from 7 mm to 80 mm. EBUS-FNA identified malignant cells in 13 lesions and benign cells in two.

Conclusions: EBUS-FNA is a promising technique for lymph node staging of lung cancer as well as for the primary diagnosis of solid lesions located adjacent to the trachea and main bronchi and not accessible by other methods apart from surgical intervention.

  • endoscopic transbronchial ultrasound guided biopsy
  • endoscopic ultrasonography
  • lung cancer
  • fine needle aspiration
  • diagnosis
  • EBUS-FNA, endoscopic transbronchial ultrasonography with fine needle aspiration biopsy
  • EUS-FNA, endoscopic ultrasonography with fine needle aspiration biopsy
  • PET, positron emission tomography
  • NSCLC, non-small cell lung cancer
  • SCLC, small cell lung cancer
View Full Text

Statistics from Altmetric.com

Footnotes

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.