▴ Holland AE, Wilson JW, Kotsimbos TC, et al. Metabolic alkalosis contributes to acute hypercapnic respiratory failure in adult cystic fibrosis. Chest2003;124:490–3
Patients admitted over a 1 year period with acute exacerbations of cystic fibrosis (CF) and hypercapnia (Paco2 ⩾45 mm Hg, n=14) were compared with a control group with hypercapnic exacerbations of COPD (n=49). The CF group were significantly younger (23 v …