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The pulmonary physician in critical care • 5: Acute lung injury and the acute respiratory distress syndrome: definitions and epidemiology
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  • Published on:
    Re : Tissue Oxygenation-oriented Approach to Patients with ARDS, author's response

    Dear Editor

    I would like to thank Dr M Ghrew for his interest in my letter. I agree that a restrictive strategy of red-cell transfusion, in which haemoglobin is maintained at 7–9 g per deciliter, is at least as effective as and possibly superior to a liberal transfusion strategy, in which haemoglobin is maintained at 10–12 g per deciliter. Hebert and his colleagues in the Canadian Critical Care Trials Group reporte...

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    Conflict of Interest:
    None declared.
  • Published on:
    Re: Tissue Oxygenation - Oriented Approach to Patients With ARDS
    • Murad Ghrew, Consultant in respiratory and critical care medicine

    Dear Editor

    MA Abdelkader suggested that Oxygen delivery can be ensured through supra-normal cardiac output and optimisation of haemoglobin level and therefore tissue oxygenation could be improved.[1]

    Although the hypothesis might be sound and biologically plausible, however, I would like to make the following remarks. Un-cautious interpretation of this may imply that blood transfusion to maintain haemogl...

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    Conflict of Interest:
    None declared.
  • Published on:
    Tissue Oxygenation - Oriented Approach to Patients With ARDS

    Dear Editor

    Despite the great advances in critical care medicine, mortality of ARDS is still high. Protective ventilatory strategy - utilizing lower tidal volumes - has been used to reduce mortality of ARDS. Both conventional and protective ventialtory strategies aim to achieve satisfactory arterial rather than tissue oxygenation.According to protective strategy, PEEP is used - even with acceptable SPO2...

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    Conflict of Interest:
    None declared.