Regulation of the effects of TGF-β1 by activation of latent TGF-β1 and differential expression of TGF-β receptors (TβR-I and TβR-II) in idiopathic pulmonary fibrosis

N Khalil; T V Parekh; R O'Connor; N Antman; W Kepron; T Yehaulaeshet; Y D Xu; L I Gold

doi:10.1136/thorax.56.12.907

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Original article

Regulation of the effects of TGF-β1 by activation of latent TGF-β1 and differential expression of TGF-β receptors (TβR-I and TβR-II) in idiopathic pulmonary fibrosis

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	Abstract	Full	Pdf
Nov 2001	70	91	43
Dec 2001	30	95	34
Jan 2002	45	130	28
Feb 2002	3	56	22
Mar 2002	12	65	23
Apr 2002	8	46	21
May 2002	3	30	9
Jun 2002	2	30	7
Jul 2002	4	25	10
Aug 2002	5	29	13
Sep 2002	2	22	7
Oct 2002	2	30	15
Nov 2002	3	20	15
Dec 2002	2	27	24
Jan 2003	0	16	23
Feb 2003	1	19	18
Mar 2003	8	19	11
Apr 2003	3	30	24
May 2003	4	18	19
Jun 2003	3	10	12
Jul 2003	22	30	19
Aug 2003	22	30	10
Sep 2003	20	23	16
Oct 2003	19	43	13
Nov 2003	23	28	8
Dec 2003	27	23	7
Jan 2004	29	18	17
Feb 2004	10	22	20
Mar 2004	17	26	12
Apr 2004	17	27	12
May 2004	41	59	14
Jun 2004	33	51	3
Jul 2004	46	49	5
Aug 2004	28	54	11
Sep 2004	36	62	14
Oct 2004	20	58	14
Nov 2004	15	43	18
Dec 2004	17	31	12
Jan 2005	16	44	17
Feb 2005	13	44	20
Mar 2005	11	42	15
Apr 2005	19	31	37
May 2005	11	32	26
Jun 2005	11	27	18
Jul 2005	8	18	8
Aug 2005	11	18	17
Sep 2005	11	30	12
Oct 2005	15	35	16
Nov 2005	6	35	14
Dec 2005	8	29	22
Jan 2006	14	24	15
Feb 2006	5	20	12
Mar 2006	3	37	26
Apr 2006	11	19	17
May 2006	2	10	11
Jun 2006	1	17	8
Jul 2006	2	12	12
Aug 2006	0	20	3
Sep 2006	2	29	18
Oct 2006	8	23	14
Nov 2006	12	27	19
Dec 2006	8	16	11
Jan 2007	9	11	21
Feb 2007	12	25	19
Mar 2007	18	35	27
Apr 2007	12	13	7
May 2007	20	5	8
Jun 2007	18	9	4
Jul 2007	6	10	13
Aug 2007	12	9	5
Sep 2007	12	6	10
Oct 2007	10	8	14
Nov 2007	7	3	7
Dec 2007	7	6	7
Jan 2008	5	4	3
Feb 2008	9	21	16
Mar 2008	25	12	9
Apr 2008	11	9	7
May 2008	12	4	5
Jun 2008	13	3	2
Jul 2008	26	9	6
Aug 2008	33	4	2
Sep 2008	41	2	3
Oct 2008	23	8	5
Nov 2008	15	8	3
Dec 2008	8	7	5
Jan 2009	12	4	2
Feb 2009	14	1	2
Mar 2009	22	13	10
Apr 2009	18	7	7
May 2009	10	6	8
Jun 2009	20	4	5
Jul 2009	11	6	3
Aug 2009	6	8	3
Sep 2009	19	6	7
Oct 2009	36	12	10
Nov 2009	29	5	0
Dec 2009	10	2	1
Jan 2010	8	2	2
Feb 2010	15	6	8
Mar 2010	22	3	0
Apr 2010	13	8	9
May 2010	7	4	3
Jun 2010	4	6	8
Jul 2010	13	8	9
Aug 2010	12	2	2
Sep 2010	11	4	0
Oct 2010	21	9	5
Nov 2010	13	4	2
Dec 2010	5	3	1
Jan 2011	11	7	3
Feb 2011	9	7	3
Mar 2011	23	4	2
Apr 2011	11	6	4
May 2011	10	4	4
Jun 2011	17	8	4
Jul 2011	17	2	2
Aug 2011	20	9	4
Sep 2011	16	7	1
Oct 2011	24	6	6
Nov 2011	22	9	9
Dec 2011	21	16	15
Jan 2012	30	20	18
Feb 2012	19	15	8
Mar 2012	19	16	7
Apr 2012	15	16	6
May 2012	14	18	13
Jun 2012	20	19	5
Jul 2012	17	6	6
Aug 2012	10	8	4
Sep 2012	14	13	10
Oct 2012	29	13	10
Nov 2012	19	13	5
Dec 2012	15	15	12
Jan 2013	24	7	8
Feb 2013	38	5	10
Mar 2013	15	8	8
Apr 2013	14	8	5
May 2013	11	12	11
Jun 2013	5	9	6
Jul 2013	12	15	11
Aug 2013	3	8	3
Sep 2013	15	6	10
Oct 2013	14	7	7
Nov 2013	21	6	6
Dec 2013	20	6	7
Jan 2014	12	15	11
Feb 2014	14	15	9
Mar 2014	32	9	4
Apr 2014	14	26	7
May 2014	19	20	16
Jun 2014	20	6	6
Jul 2014	19	20	6
Aug 2014	10	12	6
Sep 2014	16	7	6
Oct 2014	9	9	9
Nov 2014	14	8	10
Dec 2014	10	7	7
Jan 2015	15	6	3
Feb 2015	6	2	4
Mar 2015	11	18	10
Apr 2015	4	10	5
May 2015	3	4	4
Jun 2015	8	15	3
Jul 2015	5	23	13
Aug 2015	13	17	7
Sep 2015	22	22	2
Oct 2015	7	3	3
Nov 2015	22	17	8
Dec 2015	28	16	13
Jan 2016	34	14	8
Feb 2016	14	7	2
Mar 2016	16	3	6
Apr 2016	12	5	5
May 2016	12	2	4
Jun 2016	10	8	15
Jul 2016	14	14	14
Aug 2016	14	6	0
Sep 2016	13	4	3
Oct 2016	26	11	10
Nov 2016	25	16	13
Dec 2016	11	11	12
Jan 2017	38	13	15
Feb 2017	4	15	10
Mar 2017	10	10	4
Apr 2017	4	12	7
May 2017	4	13	2
Jun 2017	9	16	11
Jul 2017	16	12	4
Aug 2017	27	25	9
Sep 2017	31	21	12
Oct 2017	26	18	15
Nov 2017	26	22	12
Dec 2017	31	25	11
Jan 2018	25	21	5
Feb 2018	23	17	5
Mar 2018	21	13	18
Apr 2018	22	18	5
May 2018	61	54	2
Jun 2018	38	34	6
Jul 2018	14	14	11
Aug 2018	39	35	2
Sep 2018	53	53	5
Oct 2018	69	69	16
Nov 2018	89	89	5
Dec 2018	75	73	3
Jan 2019	60	60	6
Feb 2019	51	51	7
Mar 2019	36	36	11
Apr 2019	25	17	11
May 2019	40	32	11
Jun 2019	27	20	7
Jul 2019	25	14	13
Aug 2019	15	14	8
Sep 2019	12	10	5
Oct 2019	21	17	9
Nov 2019	19	11	7
Dec 2019	40	28	8
Jan 2020	22	14	5
Feb 2020	14	11	8
Mar 2020	22	18	6
Apr 2020	5	5	9
May 2020	21	15	8
Jun 2020	20	15	9
Jul 2020	13	11	3
Aug 2020	15	15	9
Sep 2020	29	26	3
Oct 2020	31	27	9
Nov 2020	29	24	9
Dec 2020	34	30	6
Jan 2021	21	21	14
Feb 2021	28	22	13
Mar 2021	48	37	7
Apr 2021	56	52	9
May 2021	31	25	13
Jun 2021	42	42	10
Jul 2021	23	23	12
Aug 2021	28	27	10
Sep 2021	24	23	23
Oct 2021	47	33	34
Nov 2021	31	23	27
Dec 2021	27	15	14
Jan 2022	43	27	9
Feb 2022	21	20	5
Mar 2022	40	33	19
Apr 2022	63	49	8
May 2022	56	52	29
Jun 2022	51	40	20
Jul 2022	37	30	5
Aug 2022	43	33	8
Sep 2022	54	44	26
Oct 2022	51	47	9
Nov 2022	80	54	10
Dec 2022	29	23	7
Jan 2023	54	46	13
Feb 2023	110	93	12
Mar 2023	47	33	11
Apr 2023	35	17	12
May 2023	48	26	12
Jun 2023	34	20	15
Jul 2023	32	23	10
Aug 2023	46	27	13
Sep 2023	31	17	11
Oct 2023	46	31	5
Nov 2023	45	41	10
Dec 2023	67	60	6
Jan 2024	39	39	10
Feb 2024	44	38	9
Mar 2024	68	39	34
Total	5824	5808	2729

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