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Superior vena cava obstruction caused by radiation induced venous fibrosis
  1. J W G Van Puttena,
  2. N J J Schlosserb,
  3. Z Vujaskovicc,
  4. A H D Van Der Leestc,
  5. H J M Groena
  1. aDepartment of Pulmonary Medicine, University Hospital, Groningen, The Netherlands, bDepartment of Pulmonary Medicine, University Hospital, Utrecht, The Netherlands, cDepartment of Radiotherapy, University Hospital, Groningen, The Netherlands
  1. Dr J W G van Putten, Department of Pulmonary Medicine, University Hospital, Hanzeplein 1, 9752 GZ Groningen, The Netherlands

Abstract

Superior vena cava syndrome is most often caused by lung carcinoma. Two cases are described in whom venous obstruction in the superior mediastinum was caused by local vascular fibrosis due to radiotherapy five and seven years earlier. The development of radiation injury to greater vessels is discussed, together with the possibilities for treatment of superior vena cava syndrome.

  • venous obstruction
  • radiation fibrosis
  • superior vena cava syndrome

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