Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations

Angshu Bhowmik; Terence A R Seemungal; Raymond J Sapsford; Jadwiga A Wedzicha

doi:10.1136/thorax.55.2.114

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Original article

Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations

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Online download statistics by month: January 2000 to August 2024

	Abstract	Full	Pdf
Jan 2000	111	86	50
Feb 2000	81	142	59
Mar 2000	16	48	23
Apr 2000	12	41	14
May 2000	10	34	20
Jun 2000	4	19	13
Jul 2000	6	21	13
Aug 2000	7	20	20
Sep 2000	13	14	19
Oct 2000	7	12	8
Nov 2000	10	16	14
Dec 2000	9	13	7
Jan 2001	7	16	12
Feb 2001	9	36	35
Mar 2001	6	21	19
Apr 2001	6	19	7
May 2001	2	44	2
Jun 2001	11	14	13
Jul 2001	3	35	22
Aug 2001	7	16	11
Sep 2001	6	12	3
Oct 2001	12	31	15
Nov 2001	8	44	11
Dec 2001	17	25	31
Jan 2002	13	23	7
Feb 2002	6	45	25
Mar 2002	12	24	12
Apr 2002	16	35	29
May 2002	15	27	15
Jun 2002	6	34	19
Jul 2002	8	28	16
Aug 2002	7	24	8
Sep 2002	13	44	27
Oct 2002	11	24	25
Nov 2002	31	63	62
Dec 2002	5	33	19
Jan 2003	9	29	34
Feb 2003	8	28	26
Mar 2003	24	36	23
Apr 2003	26	31	35
May 2003	17	43	28
Jun 2003	14	38	28
Jul 2003	26	39	26
Aug 2003	27	40	18
Sep 2003	22	55	23
Oct 2003	33	60	25
Nov 2003	25	44	18
Dec 2003	18	53	25
Jan 2004	34	53	37
Feb 2004	15	30	24
Mar 2004	34	75	51
Apr 2004	36	59	24
May 2004	47	78	31
Jun 2004	46	90	24
Jul 2004	53	77	30
Aug 2004	48	78	32
Sep 2004	60	82	42
Oct 2004	27	63	60
Nov 2004	53	57	46
Dec 2004	27	56	51
Jan 2005	31	49	19
Feb 2005	37	54	33
Mar 2005	54	47	37
Apr 2005	34	71	33
May 2005	22	44	26
Jun 2005	36	48	32
Jul 2005	38	50	25
Aug 2005	20	36	25
Sep 2005	24	42	30
Oct 2005	17	40	24
Nov 2005	40	41	47
Dec 2005	24	36	23
Jan 2006	18	53	30
Feb 2006	23	84	34
Mar 2006	23	69	39
Apr 2006	43	55	42
May 2006	37	38	33
Jun 2006	42	28	22
Jul 2006	38	33	25
Aug 2006	25	40	21
Sep 2006	23	42	31
Oct 2006	54	45	35
Nov 2006	50	37	31
Dec 2006	44	36	24
Jan 2007	47	42	37
Feb 2007	51	43	36
Mar 2007	53	69	37
Apr 2007	62	19	22
May 2007	51	24	14
Jun 2007	24	10	11
Jul 2007	20	16	17
Aug 2007	36	15	5
Sep 2007	32	31	24
Oct 2007	47	12	14
Nov 2007	45	22	15
Dec 2007	37	30	18
Jan 2008	41	17	15
Feb 2008	41	10	16
Mar 2008	74	16	14
Apr 2008	38	11	20
May 2008	17	7	14
Jun 2008	40	6	11
Jul 2008	22	8	11
Aug 2008	28	7	8
Sep 2008	34	14	19
Oct 2008	33	8	15
Nov 2008	37	19	13
Dec 2008	34	15	19
Jan 2009	39	15	12
Feb 2009	67	13	18
Mar 2009	80	12	21
Apr 2009	56	15	17
May 2009	63	11	26
Jun 2009	38	6	16
Jul 2009	46	3	5
Aug 2009	34	6	8
Sep 2009	39	6	10
Oct 2009	69	7	18
Nov 2009	62	5	13
Dec 2009	38	7	13
Jan 2010	44	13	14
Feb 2010	55	8	14
Mar 2010	72	18	17
Apr 2010	45	18	10
May 2010	43	16	7
Jun 2010	38	16	12
Jul 2010	27	11	10
Aug 2010	38	11	16
Sep 2010	33	7	10
Oct 2010	48	14	14
Nov 2010	38	20	15
Dec 2010	24	17	10
Jan 2011	43	17	8
Feb 2011	27	17	11
Mar 2011	57	29	23
Apr 2011	64	13	21
May 2011	56	6	13
Jun 2011	28	2	15
Jul 2011	43	6	12
Aug 2011	30	7	10
Sep 2011	45	13	19
Oct 2011	84	12	9
Nov 2011	57	17	19
Dec 2011	46	30	27
Jan 2012	56	14	24
Feb 2012	51	9	17
Mar 2012	52	20	28
Apr 2012	40	10	23
May 2012	47	22	28
Jun 2012	53	23	24
Jul 2012	45	28	27
Aug 2012	39	17	26
Sep 2012	56	21	41
Oct 2012	85	42	30
Nov 2012	71	28	26
Dec 2012	76	20	22
Jan 2013	76	31	27
Feb 2013	59	20	13
Mar 2013	83	45	24
Apr 2013	81	26	31
May 2013	91	32	30
Jun 2013	54	19	21
Jul 2013	44	15	14
Aug 2013	44	13	16
Sep 2013	54	9	32
Oct 2013	101	27	27
Nov 2013	75	29	26
Dec 2013	67	18	23
Jan 2014	88	30	50
Feb 2014	63	35	28
Mar 2014	81	24	35
Apr 2014	99	27	38
May 2014	83	30	40
Jun 2014	67	29	34
Jul 2014	70	38	28
Aug 2014	66	22	17
Sep 2014	68	26	24
Oct 2014	75	28	27
Nov 2014	72	20	16
Dec 2014	62	21	12
Jan 2015	70	23	20
Feb 2015	60	39	24
Mar 2015	63	52	27
Apr 2015	79	37	26
May 2015	65	24	20
Jun 2015	45	19	12
Jul 2015	51	21	21
Aug 2015	69	24	18
Sep 2015	67	27	15
Oct 2015	36	31	12
Nov 2015	75	56	24
Dec 2015	46	31	23
Jan 2016	169	27	21
Feb 2016	105	21	19
Mar 2016	69	27	30
Apr 2016	75	33	29
May 2016	77	22	32
Jun 2016	76	26	31
Jul 2016	73	27	35
Aug 2016	76	23	43
Sep 2016	72	14	24
Oct 2016	83	36	25
Nov 2016	100	37	30
Dec 2016	82	19	13
Jan 2017	89	21	18
Feb 2017	46	19	26
Mar 2017	66	44	21
Apr 2017	55	61	28
May 2017	39	64	25
Jun 2017	59	61	20
Jul 2017	102	57	17
Aug 2017	159	75	31
Sep 2017	149	95	22
Oct 2017	148	72	17
Nov 2017	142	53	25
Dec 2017	98	24	11
Jan 2018	131	33	15
Feb 2018	152	39	21
Mar 2018	222	132	26
Apr 2018	165	57	20
May 2018	96	44	16
Jun 2018	112	70	17
Jul 2018	100	46	16
Aug 2018	122	76	23
Sep 2018	131	75	33
Oct 2018	145	89	21
Nov 2018	165	97	31
Dec 2018	130	94	17
Jan 2019	162	78	28
Feb 2019	113	66	19
Mar 2019	96	49	27
Apr 2019	96	53	25
May 2019	125	51	36
Jun 2019	58	32	20
Jul 2019	70	44	20
Aug 2019	77	43	24
Sep 2019	95	53	21
Oct 2019	77	58	32
Nov 2019	106	72	37
Dec 2019	75	33	21
Jan 2020	73	45	21
Feb 2020	70	42	19
Mar 2020	68	49	19
Apr 2020	80	44	36
May 2020	65	45	31
Jun 2020	73	44	24
Jul 2020	49	37	12
Aug 2020	50	40	16
Sep 2020	83	67	17
Oct 2020	95	59	37
Nov 2020	74	48	15
Dec 2020	80	64	7
Jan 2021	88	52	18
Feb 2021	68	44	14
Mar 2021	95	47	24
Apr 2021	78	48	17
May 2021	67	46	14
Jun 2021	46	46	9
Jul 2021	74	75	25
Aug 2021	72	72	22
Sep 2021	67	67	17
Oct 2021	102	74	26
Nov 2021	48	35	21
Dec 2021	81	67	15
Jan 2022	64	48	17
Feb 2022	37	30	13
Mar 2022	60	53	22
Apr 2022	79	60	23
May 2022	82	70	18
Jun 2022	61	60	12
Jul 2022	51	40	10
Aug 2022	100	63	19
Sep 2022	108	86	21
Oct 2022	152	98	25
Nov 2022	94	63	15
Dec 2022	107	73	8
Jan 2023	140	114	10
Feb 2023	112	78	17
Mar 2023	110	90	13
Apr 2023	87	70	18
May 2023	71	45	29
Jun 2023	66	30	13
Jul 2023	72	44	24
Aug 2023	196	184	14
Sep 2023	113	90	15
Oct 2023	87	65	16
Nov 2023	151	108	11
Dec 2023	584	249	14
Jan 2024	164	129	56
Feb 2024	151	129	16
Mar 2024	128	109	70
Apr 2024	105	77	28
May 2024	484	388	17
Jun 2024	216	20	1
Jul 2024	729	51	1
Aug 2024	191	31	3
Total	19557	12306	6540

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