Article Text

Download PDFPDF

Gorham's syndrome: a usually fatal cause of pleural effusion treated successfully with radiotherapy.
  1. K. D. McNeil,
  2. K. M. Fong,
  3. Q. J. Walker,
  4. P. Jessup,
  5. P. V. Zimmerman
  1. Department of Thoracic Medicine, Prince Charles Hospital, Chermside, Brisbane, Australia.


    A 21 year old man presented with a right sided pleural effusion. Destruction of the 11th and 12th right ribs and adjacent vertebral bodies was noted on computed tomographic scanning. An open rib biopsy revealed the histopathological changes of Gorham's syndrome. In view of the progressive vertebral destruction and inevitable spinal cord compromise, he was treated with high dose radiotherapy. The process was arrested and he remains well with no signs of recurrence after four years. Pleural effusion and vertebral destruction complicating Gorham's syndrome carry a poor prognosis but, in this case, high dose radiotherapy has been effective in controlling both the effusion and the progressive bony destruction.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Linked Articles