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Bronchiectasis and homozygous (P1ZZ) alpha 1-antitrypsin deficiency in a young man.
  1. W Rodriguez-Cintron,
  2. K Guntupalli,
  3. A E Fraire
  1. Department of Pulmonary Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.


    Pulmonary complications of alpha 1-antitrypsin deficiency are most commonly manifested by panlobular emphysema. This report describes histologically proven bronchiectasis in a 21 year old man with massive haemoptysis and homozygous deficiency of alpha 1-antitrypsin. Neither panlobular emphysema nor cirrhosis of the liver were present. Bronchiectasis must be considered part of the spectrum of the pulmonary pathology that may be encountered in individuals with alpha 1-antitrypsin deficiency.

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