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Research Article
Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens.
  1. D R Baldwin,
  2. J M Andrews,
  3. J P Ashby,
  4. R Wise,
  5. D Honeybourne
  1. Department of Thoracic Medicine, Dudley Road Hospital, Birmingham.

    Abstract

    In a study of 58 patients the concentrations of cefixime, a new oral cephem antibiotic, in bronchial mucosa were 35-40% of the concentrations found in simultaneously collected serum samples. The antibiotic was often undetectable in sputum despite a highly sensitive assay.

    https://doi.org/10.1136/thx.45.5.401

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