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Occupational asthma in a pharmaceutical worker exposed to hydralazine.
  1. B Perrin,
  2. J L Malo,
  3. A Cartier,
  4. S Evans,
  5. J Dolovich
  1. Department of Chest Medicine, Hôpital du Sacré-Coeur, West Gouin, Montreal, Canada.


    A pharmaceutical worker developed asthma when exposed to hydralazine, an antihypertensive drug. The diagnosis of occupational asthma was supported by specific inhalation challenges, which produced a late asthmatic reaction and an increase in bronchial responsiveness. No evidence of an IgE or an IgG dependent mechanism could be found.

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