Article Text

Download PDFPDF
Prevention of fever and gram negative infection after open heart surgery by antiendotoxin.
  1. R Freeman,
  2. F K Gould

    Abstract

    Naturally occurring preoperative antibody to enteric Gram negative bacilli (Escherichia coli agglutinins or antiendotoxin, or both) in 30 patients who had had open heart surgery was associated with a significantly lower incidence of early postoperative fever and postoperative Gram negative infection than occurred in 56 patients without preoperative antibodies. The protective effect was shown to be associated with antiendotoxin rather than antibody to the somatic antigen of the bacteria. Active or passive immunisation of patients having open heart surgery against endotoxin is likely to decrease significantly the morbidity after cardiopulmonary bypass.

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.