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Effects of naftidrofuryl on breathlessness and exercise tolerance in chronic bronchitis.
  1. A J Williams,
  2. J Osman,
  3. C Skinner


    Naftidrofuryl enhances oxidative phosphorylation and might therefore be expected to improve exercise tolerance and breathlessness in advanced chronic bronchitis. This hypothesis was tested in a four-week placebo-controlled trial in 11 bronchitic patients. Seven patients completed the study. There was no evidence of any benefit from naftidrofuryl either subjectively or after a 12-minute walking test.

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