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Serum hepatitis after open-heart surgery
  1. Eunice Lockey1,
  2. Yvonne Cossart,
  3. Lorenzo Gonzalez-Lavin
  1. National Heart Hospital, Colindale, London
  2. Virus Reference Laboratory, Colindale, London


    Ten cases of serum hepatitis occurring after open-heart surgery at the National Heart Hospital, London are reported. The incidence seemed to be rising and was at least 2% before antigen-screened blood became available. Investigation of 135 patients for the presence of Australia antigen and antibody showed that five (3·7%) had responses to exposure to the infective agent. All were and remained clinically well, but such patients may constitute a source of infection. Since tested blood has been used no hepatitis cases have been recognized.

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    • 1 1 Please address all correspondence to: Dr. E. Lockey, National Heart Hospital, Westmoreland Street, London W1M 8BA