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Inappropriate antidiuretic hormone secretion in oat-cell carcinoma of bronchus
  1. A. H. G. Munro,
  2. G. K. Crompton1
  1. Respiratory Diseases Unit, Northern General Hospital, Edinburgh
  2. Department of Respiratory Diseases, University of Edinburgh

    Aggravation of hyponatraemia by intravenous cyclophosphamide


    A patient with hyponatraemia associated with an oat-cell carcinoma of the bronchus is described. Treatment with intermittent large doses of cyclophosphamide intensified the hyponatraemia. An explanation of this previously undescribed phenomenon is suggested.

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