Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …

Bronchoalveolar lavage (BAL) has become a standard diagnostic procedure for the majority
of patients with interstitial disease. The technique is safe, minimally invasive, and reveals …

Pirfenidone is one of two approved therapies for the treatment of idiopathic pulmonary
fibrosis (IPF). Randomised controlled clinical trials and subsequent post hoc analyses have …

This document is an international evidence-based guideline on the diagnosis and
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …

Background Nintedanib (formerly known as BIBF 1120) is an intracellular inhibitor that
targets multiple tyrosine kinases. A phase 2 trial suggested that treatment with 150 mg of …

Background: In 2002 the American Thoracic Society/European Respiratory Society
(ATS/ERS) classification of idiopathic interstitial pneumonias (IIPs) defined seven specific …

Background Idiopathic pulmonary fibrosis is a progressive and fatal lung disease with
inevitable loss of lung function. The CAPACITY programme (studies 004 and 006) was …

Background Idiopathic pulmonary fibrosis is a chronic progressive disorder with a poor
prognosis. Methods We conducted a double-blind, randomized, placebo-controlled …

Background Idiopathic pulmonary fibrosis is a progressive lung disease with a high mortality
rate. Because the signaling pathways activated by several tyrosine kinase receptors have …

Background: The clinical utility of bronchoalveolar lavage fluid (BAL) cell analysis for the
diagnosis and management of patients with interstitial lung disease (ILD) has been a subject …