Antibiotic Management of Lung Infections in Cystic Fibrosis. I. The Microbiome, Methicillin-Resistant Staphylococcus aureus, Gram-Negative Bacteria, and Multiple …
JF Chmiel, TR Aksamit, SH Chotirmall… - Annals of the …, 2014 - atsjournals.org
Despite significant advances in treatment strategies targeting the underlying defect in cystic
fibrosis (CF), airway infection remains an important cause of lung disease. In this two-part …
fibrosis (CF), airway infection remains an important cause of lung disease. In this two-part …
Evidence-based management of paediatric primary spontaneous pneumothorax
PD Robinson, P Cooper, SC Ranganathan - Paediatric respiratory reviews, 2009 - Elsevier
The exact incidence of paediatric primary spontaneous pneumothorax (PSP) is unclear,
although PSP incidence in the general population is between 6 and 18 per 100000. PSP …
although PSP incidence in the general population is between 6 and 18 per 100000. PSP …
Early lung disease in infants and preschool children with cystic fibrosis. What have we learned and what should we do about it?
The past decade has seen significant advances in understanding of the pathogenesis and
progression of lung disease in cystic fibrosis (CF). Pulmonary inflammation, infection, and …
progression of lung disease in cystic fibrosis (CF). Pulmonary inflammation, infection, and …
Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening
PD Sly, S Brennan, C Gangell, N De Klerk… - American journal of …, 2009 - atsjournals.org
Rationale: The promise of newborn screening (NBS) for cystic fibrosis (CF) has not been
fully realized, and the extent of improvement in respiratory outcomes is unclear. We …
fully realized, and the extent of improvement in respiratory outcomes is unclear. We …
Progression of early structural lung disease in young children with cystic fibrosis assessed using CT
LS Mott, J Park, CP Murray, CL Gangell, NH de Klerk… - Thorax, 2012 - thorax.bmj.com
Background Cross-sectional studies implicate neutrophilic inflammation and pulmonary
infection as risk factors for early structural lung disease in infants and young children with …
infection as risk factors for early structural lung disease in infants and young children with …
[HTML][HTML] A Three-Way Comparison of Tuberculin Skin Testing, QuantiFERON-TB Gold and T-SPOT.TB in Children
Background There are limited data comparing the performance of the two commercially
available interferon gamma (IFN-γ) release assays (IGRAs) for the diagnosis of tuberculosis …
available interferon gamma (IFN-γ) release assays (IGRAs) for the diagnosis of tuberculosis …
PRAGMA-CF. A quantitative structural lung disease computed tomography outcome in young children with cystic fibrosis
T Rosenow, MCJ Oudraad, CP Murray… - American journal of …, 2015 - atsjournals.org
Rationale: Chest computed tomography (CT) is the gold standard for demonstrating cystic
fibrosis (CF) airway disease. However, there are no standardized outcome measures …
fibrosis (CF) airway disease. However, there are no standardized outcome measures …
Performance of a whole blood interferon gamma assay for detecting latent infection with Mycobacterium tuberculosis in children
Background: The diagnosis of latent Mycobacterium tuberculosis (MTB) infection with a
tuberculin skin test (TST) in children is complicated by the potential influence of prior …
tuberculin skin test (TST) in children is complicated by the potential influence of prior …
[HTML][HTML] Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children
MS Muhlebach, BT Zorn, CR Esther, JE Hatch… - PLoS …, 2018 - journals.plos.org
The cystic fibrosis (CF) lung microbiome has been studied in children and adults; however,
little is known about its relationship to early disease progression. To better understand the …
little is known about its relationship to early disease progression. To better understand the …
Lung function in infants with cystic fibrosis diagnosed by newborn screening
BM Linnane, GL Hall, G Nolan, S Brennan… - American journal of …, 2008 - atsjournals.org
Rationale: Progressive lung damage in cystic fibrosis (CF) starts in infancy, and early
detection may aid preventative strategies. Objectives: To measure lung function in infants …
detection may aid preventative strategies. Objectives: To measure lung function in infants …